Methods of Ozone Therapy
Presently there are nine methods of ozone therapy in medical practice namely:
Direct intra-arterial and intravenous application
An ozone/oxygen mixture is slowly injected into an artery or vein with a hypodermic syringe. This method is used
primarily for arterial circulatory disorders. According to Gerard V. Sunnen, M.D., “Due to accidents produced by
too rapid introduction of the gas mixture into the circulation, this technique is now rarely used” (1988).
First pioneered by Payr and Aubourg in the 1930’s, a mixture of ozone and oxygen is introduced through the
rectum and absorbed into the body through the intestine. Used for a wide variety of health problems, this
method is considered one of the safest. In a typical treatment for ulcerative colitis, for example, 75 micrograms
of ozone per milliliter of oxygen are used (treatment begins with 50ml of oxygen which can be increased
slowly to 500 ml per treatment) 16 While administered under medical supervision in Germany, Russia and
Cuba, a growing number of private individuals in the United States use this method for self-treatment for
cancer, HIV-related problems and other diseases.
A small amount of an ozone and oxygen mixture (up to 10 ml) are injected into the patient (usually in the
buttocks) like a normal injection would be. This method is commonly used to treat allergies and inflammatory
diseases. Intramuscular injections are sometimes utilized as an adjunct to cancer therapies in Europe.
Major and minor autohemotherapy
Used since the 1960’s, minor autohaemotherapy involves removing a small amount (usually 10 ml) of the
patient’s blood from a vein with a hypodermic syringe. The blood is then treated with ozone and oxygen, and
given back to the patient with an intramuscular injection. Thus the blood and ozone becomes a type of autovaccine given to the patient that is derived from their own cells, thus forming a unique vaccine that can be
very specific and effective in treating the patient’s health problem. Major autohaemotherapy calls for the
removal of between 50-100 ml of the patient’s blood. Ozone and oxygen are then bubbled into the blood for
several minutes, and then the ozonated blood is re-introduced into a vein. These methods have been used to
treat a wide variety of health problems, including herpes, arthritis, cancer, heart disease and HIV-infection.
It is probably the most commonly used type of ozone therapy today
This method calls for ozone gas to be bubbled through water, and the water is used externally to bathe
wounds, burns and slow-healing skin infections. It is also used as a disinfectant by dentists who perform
dental surgery. In Russia, physicians are using ozonated water to irrigate body cavities during surgery. In
both Russia and Cuba, ozonated water is used to treat a wide variety of intestinal and gynecological problems,
including ulcerative colitis, duodenal ulcers, gastritis, diarrhea and vulvovaginitis (Proceedings of the First
Iberolatinamerican Congress on Ozone Applications, 1990).
In this method, ozone gas is bubbled through water and the mixture is injected directly between the joints. It
is used primarily by physicians in Germany, Russia and Cuba to treat arthritis, rheumatism and other joint
This non-invasive method uses a specially made plastic bag that is placed around the area to be treated. An
ozone/oxygen mixture is pumped into the bag and the mixture is absorbed into the body through the skin.
Ozone bagging is primarily recommended for treating leg ulcers, gangrene, fungal infections, burns and
Used primarily to treat skin problems, ozone gas is added to olive oil and applied as a balm or salve for longterm, low-dose exposure.
Inhalation of ozone
The lungs are the organs most sensitive to ozone. Physicians who use medical ozone warn that inhaling
ozone into the lungs can bring about alterations in the density of the lung tissue, can damage delicate lung
membranes, irritate the epithelium [the surface layer of mucus] in the trachea and bronchi, and can lead to emphysema. They caution users that no ozone should escape into the room in which it is being used. Modern
medical ozone generators are specially designed so that the accidental escape of ozone gas cannot take place.
Dr. Stephen A. Levine, the co-author of Antioxidant Adaptation, cautions people against using commercial
air purifiers which generate small amounts of ozone to clean the air, since ozone should not be inhaled.